variable domain वाक्य
उदाहरण वाक्य
मोबाइल
- The variable domain of syndecan-4 could be a site of self-association.
- "' V-set domains "'are Ig-like domains resembling the antibody variable domain.
- As a consequence, any daughter B cells will acquire slight amino acid differences in the variable domains of their antibody chains.
- An alternative approach is to split the dimeric variable domains from common immunoglobulin G ( IgG ) from humans or mice into monomers.
- Specialized constraint propagation techniques for cumulative constraints exists; different techniques are used depending on which variable domains are already reduced to a single value.
- Another amide ring occurs at the interior of the variable domains of some Immunoglobulin G antibodies and assists in linking the two beta-sheets.
- Syndecan-4 also binds to phosphatidylinositol ( 4, 5 )-bisphosphate ( PIP2 ) through the variable domain and increases PKC activity ten-fold.
- There are two types of light chains : kappa and lambda, each composed of a constant domain ( CL ) and a variable domain ( VL ).
- The variable domain exon is rejoined through a process called non-homologous end joining ( NHEJ ) to the desired constant region ( ?, ? or ? ).
- Another possibility is that the toxins produced by this bacteria could act as superantigens that activate directly the T-cells over the variable domain of t-cell receptors.
- As a result of allelic exclusion, all the antigen receptors on an individual lymphocyte will have the same amino acid sequence in the variable domain of the heavy chain protein.
- Although most research into single-domain antibodies is currently based on heavy chain variable domains, Nanobodies derived from light chains have also been shown to bind specifically to target epitopes.
- The latter type is a heavy-chain antibody, an antibody lacking light chains, and can be used to produce single-domain antibodies, which are essentially the variable domain of an IgNAR.
- If the fuzzy membership functions cover 100 % of the input variable domain, then it can be proven that the behavior of the fuzzy system is fully deterministic over the entire input domain and nowhere ambiguous.
- Other types of bispecific antibodies have been designed to overcome certain problems, such as short bivalent and trivalent single-chain variable fragments ( scFvs ), fusion proteins mimicking the variable domains of two antibodies.
- The free ends of the DNA are rejoined by a process called non-homologous end joining ( NHEJ ) to link the variable domain exon to the desired downstream constant domain exon of the antibody heavy chain.
- In these rapidly dividing cells, the genes encoding the variable domains of the heavy and light chains undergo a high rate of point mutation, by a process called " somatic hypermutation " ( SHM ).
- As above, given two assignments s, t with same variable domain, we write s \ sim _ V t if s ( w ) = t ( w ) for every variable w \ in dom ( s ) \ setminus V.
- As the specificity of the antigen receptor is modulated by the variable domain of the light chain encoded by one of the immunoglobulin light chain loci, the specificities of B cells containing the same heavy chain recombination event can differ according to their light chain recombination event.
- There are five types of heavy chains : alpha, delta, epsilon, gamma and mu, all consisting of a variable domain ( VH ) and three ( in alpha, delta and gamma ) or four ( in epsilon and mu ) constant domains ( CH1 to CH4 ).
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